Pesticide properties for Iodomethane, including approvals, environmental fate, eco-toxicity and human health issues . Iodomethane can also be prepared by the reaction of methanol with aqueous hydrogen iodide: The generated iodomethane can be distilled from the reaction mixture. PubMed: Rapid quantification of urinary 11-nor-delta9-tetrahydrocannabinol-9-carboxylic acid using fast gas chromatography-mass spectrometry. Melting point determination is the thermal analysis most frequently used to characterize solid crystalline materials. All but one were industrialnot agriculturalaccidents, and the remaining case of poisoning was an apparent suicide. ??P)LU;_ka,y*O*jGu-MtA0YfoC"uFqc;^m;vx?? Linear Formula: 13 CD 3 I. CAS No. View the Full Spectrum for FREE! John Wiley & Sons, Ltd, 2005. Iodomethane, alias methyliodide, is a halogenated methane (chloromethane, methyl bromide, methyl iodide) compound, often used as an intermediate in organic synthesis in the pharmaceutical industry.Since iodide ion is a good leaving group, methyl iodide is very good Methylation reagents, commonly used in the methylation of alcohols, phenols, ketones, esters, carboxylic acids, amino compounds . http://www.docbrown.info/page13/ChemicalTests/ChemicalTestsf.htm Learn with flashcards, games, and more for free. ], colourless to pale yellow liquid with an ether-like odour. PictogramSignal word DangerHazard statement(s)H301 + H311 Toxic if swallowed or in contact with skinH314 Causes severe skin burns and eye damage.H317 May cause an allergic skin reaction.H318 Causes serious eye damage.H330 Fatal if inhaled.H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled.H335 May cause respiratory irritation.H351 Suspected of causing cancer.Precautionary statement(s)P201 Obtain special instructions before use.P202 Do not handle until all safety precautions have been read andunderstood.P260 Do not breathe dust/ fume/ gas/ mist/ Vapors/ spray.P264 Wash skin thoroughly after handling.P270 Do not eat, drink or smoke when using this product.P271 Use only outdoors or in a well-ventilated area.P272 Contaminated work clothing should not be allowed out of the workplace.P280 Wear protective gloves/ protective clothing/ eye protection/ faceprotection.P284 Wear respiratory protection.P301 + P310 + P330 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. Applications Products Services Support. ; Stearns, S.D., Multiple detector responses for gas chromatography peak identification, J. Chromatogr. A promising approach for source apportio Get all suppliers and price by the below link: Home | It is used in research and development as well as in quality control in . Boiling point or initial boiling point and boiling range: 42\u00baC: Flammability: no data available : Lower and upper explosion limit / flammability limit: no data available: Flash point: none: Auto-ignition temperature: no data available: Decomposition temperature: no data available: pH: no data . Patty's Industrial Hygiene and Toxicology. after 15 minutes of reaction, a white . Iodine forms compounds with many elements, but is less active than the other halogens. [14] The first commercial applications of MIDAS soil fumigant in California began in Fresno County, in May, 2011. Iodomethane, CH3I, is asymmetric and polar, with a boiling point of 42 C. For the substance they are working with, the melting point range is 154 C - 156 C. Tina and Jeff use a capillary tube to find the melting point ranges of their sample. Solution Synthesis of Iodine-Doped Red Phosphorus Nanoparticles for Lithium-Ion Battery Anodes. Methylation of these and related enolates can occur on the harder oxygen atom or the (usually desired) carbon atom. forces, and contact points. View the Full Spectrum for FREE! Iodomethane is an excellent substrate for SN2 substitution reactions. In its risk assessment of iodomethane, the U.S. EPA conducted an exhaustive scientific and medical literature search over the past 100 years for reported cases of human poisonings attributable to the compound. Melting point/freezing point. doi:10.1126/science.290.5493.966. A yellow solid is formed with the smell of an antiseptic, CHI 3, tri-iodomethane, melting point 119 o C. This reaction is given by the aldehyde ethanal CH 3 CHO and all ketones with the '2-one' structure R-CO-CH 3 ('methyl ketones'). United States / English; Quick Purchase; My Favorites . Methyl iodide, NIOSH: Pocket Guide to Chemical Hazards - 1993. Bromomethane, commonly known as methyl bromide, is an organobromine compound with formula C H 3 Br.This colorless, odorless, nonflammable gas is produced both industrially and biologically. (Rus. Chromatogr., 437, 1988, 33-45. umn class: Standard polar; Column length: 3 m; Column type: Packed; Start T: 100 C; CAS no: 74884; Active phase: SP-1000; Carrier gas: He; Substrate: Chromosorb W DMCS; Data type: Kovats RI; Authors: Castello, G.; Gerbino, T.C., Effect of Temperature on the Gas Chromatographic Separation of Halogenated Compounds on Polar and Non-Polar Stationary Phases, J. Wear protective gloves/protective clothing/eye protection/face protection. 3; Skin Corr. http://www.epa.gov/pesticides/factsheets/iodomethane_fs.htm. << 9.1 Information on basic physical and chemical propertiesa) Appearance Form: liquidb) Odor No data availablec) Odor Threshold No data availabled) pH No data availablee) Melting point/freezingpointMelting point/range: -64 C (-83 F) - lit.f) Initial boiling point andboiling range41 - 43 C (106 - 109 F) - lit.g) Flash point No data availableh) Evaporation rate No data availablei) Flammability (solid, gas) No data availablej) Upper/lowerflammability orexplosive limitsUpper explosion limit: 66 %(V)Lower explosion limit: 8.5 %(V)k) Vapor pressure 544 hPa (408 mmHg) at 20 C (68 F)1,660 hPa (1,245 mmHg) at 55 C (131 F)l) Vapor density 4.90 - (Air = 1.0)m) Relative density 2.28 g/cm3 at 25 C (77 F)n) Water solubility 14 g/l at 20 C (68 F)o) Partition coefficient: noctanol/waterlog Pow: 1.5 at 20 C (68 F)p) Auto-ignitiontemperatureNo data availableq) DecompositiontemperatureNo data availabler) Viscosity No data availables) Explosive properties No data availablet) Oxidizing properties No data available9.2 Other safety informationRelative Vapor density 4.90 - (Air = 1.0), 10.1 ReactivityNo data available10.2 Chemical stabilityStable under recommended storage conditions.Contains the following stabiliser(s):Copper (100 ppm)10.3 Possibility of hazardous reactionsNo data available10.4 Conditions to avoidNo data available10.5 Incompatible materialsStrong oxidizing agents, Strong bases, Oxygen10.6 Hazardous decomposition productsOther decomposition products - No data availableIn the event of fire: see section 5, 11.1 Information on toxicological effectsAcute toxicityLD50 Oral - Rat - 76 mg/kgLC50 Inhalation - Rat - 4 h - 1,300 mg/m3LD50 Dermal - Guinea pig - 800 mg/kgNo data availableSkin corrosion/irritationSkin - RabbitResult: Causes severe burns. Methyl Bromide Alternative Outreach, Fresno, CA. ), This page was last edited on 25 July 2022, at 15:15. The molecular weight of the compound is 393.73 g/mol with melting point of 121C. The molecular weight of iodoform is 393.73 g/mol. [21] In high dose acute toxicity, as may occur in industrial accidents, toxicity includes metabolic disturbance, renal failure, venous and arterial thrombosis and encephalopathy with seizures and coma, with a characteristic pattern of brain injury. IR spectra were recorded (KBr discs) on a Shimadzu FT-IR 8201 PC spectrophotometer (Kyoto, Japan). All the others you are likely to come across are liquids. Treat as a carcinogen. 52875-4, Department of Pesticide Regulation, Registration Branch, Sacramento, California. Clayton, Eds. Ed. Melting points of common materials. May cause respiratory irritation. pails, fiber and steel drums to 1 ton super sacks in full container (FCL) or truck load (T/L) quantities. The Iodomethane, also known as Iodure de methyle, is the chemical compound with the formula CH 3 I. 1; Resp. 6.1 Personal precautions, protective equipment and emergency proceduresWear respiratory protection. Stable chlorine isotope analysis of chlorinated acetic acids using gas chromatography/quadrupole mass spectrometry. [22], Iodomethane has an LD50 for oral administration to rats 76mg/kg, and in the liver it undergoes rapid conversion to S-methylglutathione.[23]. acids, acyl chlorides, ethanoic acid, and reactions to form tri-iodomethane. 01/29/2021, Occupational Safety & Health Administration, Occupational Safety and Health Administration, Outreach Training Program (10- and 30-hour Cards), OSHA Training Institute Education Centers, Appendix A, NIOSH Potential Occupational Carcinogens, Severe Storm and Flood Recovery Assistance. UNEP, Nairobi, Kenya. Povidone-iodine ointment demonstrates in vitro efficacy against biofilm formation. Iodides are generally expensive relative to the more common chlorides and bromides, though iodomethane is reasonably affordable; on a commercial scale, the more toxic dimethyl sulfate is preferred, since it is cheap and has a higher boiling point. 1975) "An updated literature search on May 30, 2007 for iodomethane poisoning produced only one additional case report." See reverse side of invoice or packing slip for additional terms and conditions of sale. Molecular Weight: 145.95. Do NOT induce vomiting.P303 + P361 + P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing.Rinse skin with water/shower.P304 + P340 + P310 IF INHALED: Remove person to fresh air and keep comfortable forbreathing. Becker, M.E. Iodide can act as a catalyst when reacting chloromethane or bromomethane with a nucleophile while iodomethane is formed in situ. It is a volatile liquid related to methane by replacement of hydrogen. Iodomethane and other organic iodine compounds do form under the conditions of a serious nuclear accident,[11] after both Chernobyl and Fukushima, Iodine-131 was detected in organic iodine compounds in Europe[12] and Japan[13] respectively. Product Classification | Journals | CDC - NIOSH Pocket Guide to Chemical Hazards - Methyl iodide It is colourless, although upon exposure to light, samples develop a purplish tinge. IF ON SKIN: Wash with plenty of s, methyl iodide, monoiodomethane, methane, iodo, methyljodid, jod-methan, methyliodide, methyljodide, iodometano, joodmethaan, metylu jodek, Electrophoresis, Western Blotting and ELISA, Chromatography and Mass Spectrometry Reagents, Laboratory Syringe Needles and Accessories, Lab Coats, Aprons, and Other Safety Apparel, Sharps Disposal Containers and Accessories, Classroom Laboratory Supplies and Consumables, Applied Biosystems TaqMan Assay and Arrays Search Tool, Applied Biosystems TaqMan Custom Assay Design Tools, Applied Biosystems Custom qPCR Primers and TaqMan Probes Tool, Chemical Storage and Management Resource Center, 01,682; 02,274; 03,202; 04,341; 05,447; 06,384; 08,342; 09,308; 15,118, Solubility in water: 14g/L (20C). Iodomethane Revision Date 06-Jan-2023 Signal Word Danger Hazard Statements Harmful in contact with skin Causes skin irritation Causes serious eye irritation . Iodomethane (methyl iodide) is widely used in organic synthesis to deliver a methyl . 7.1 Precautions for safe handlingAvoid contact with skin and eyes. Methyl iodide or iodomethane is an organic chemical compound, which appears as a dense liquid, insoluble in water, mainly used as a methylating agent. 04665. Consult a physician.In case of skin contactTake off contaminated clothing and shoes immediately. endobj Some documentation and label information may refer to the legacy brand. S-adenosyl-L-methionine + iodide -> S-adenosyl-L-homocysteine + methyl iodide. If not breathing, give artificial respiration. Rinse mouth with water. the study". In terms of chemical structure, it is related to methane by replacement of one hydrogen atom by an atom of iodine.It is naturally emitted by rice plantations in small amounts. (K) Its a combination of halogenation and oxidation and is not a definitive test for any . <> Toxic if inhaled. Quality Level. Grade For Synthesis. melting point definition: 1. the temperature at which a substance melts 2. the temperature at which a substance melts 3. the. Ohr, H.D., J.J. Sims, N.M. Grech, J.O. You can also browse global suppliers,vendor,prices,Price,manufacturers of Iodomethane(74-88-4). This recommendation is advisory only and must be evaluated by anindustrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. Buying Leads | Articles of methyl iodide are included as well. Keigwin, Richard P. "Iodomethane; Notice of Receipt of Request to Voluntarily Cancel Iodomethane Pesticide Registrations and Amend a Registration." Gloves must be inspected prior to use. until the mixture turned into a melt. . Chemsrc provides methyl iodide(CAS#:74-88-4) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Chromatogr., 126, 1976, 63-83. umn class: Semi-standard non-polar; Column length: 2.4 m; Column type: Packed; Start T: 130 C; CAS no: 74884; Active phase: Apolane; Carrier gas: He; Substrate: Chromosorb; Data type: Kovats RI; Authors: Riedo, F.; Fritz, D.; Tarjan, G.; Kovats, E.Sz., A tailor-made C87 hydrocarbon as a possible non-polar standard stationary phase for gas chromatography, J. InChi. ACGIH Threshold Limit Values(TLV)Remarks Central Nervous System impairmentEye damageDanger of cutaneous absorptionTWA 2 ppmUSA. Consult aphysician.4.2 Most important symptoms and effects, both acute and delayedThe most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 114.3 Indication of any immediate medical attention and special treatment neededNo data available, 5.1 Extinguishing mediaSuitable extinguishing mediaUse water spray, alcohol-resistant foam, dry chemical or carbon dioxide.5.2 Special hazards arising from the substance or mixtureNo data available5.3 Advice for firefightersWear self-contained breathing apparatus for firefighting if necessary.5.4 Further informationNo data available. The names are due to the presence of three iodine molecules in the compound. A, 795, 1998, 319-347. ass: Semi-standard non-polar; Column length: 2 m; Column type: Packed; Heat rate: 5 K/min; Start T: 50 C; End T: 220 C; End time: 0 min; Start time: 0 min; CAS no: 74884; Active phase: Porapack Q; Carrier gas: Nitrogen; Data type: Normal alkane RI; Authors: Zenkevich, I.G. Product Number: All applicable American Elements product codes, e.g. Meister Publishing Company, Willoughby. Its EINECS registry number is 200-819-5. These names are such due to the presence of 3 iodine molecules in the compound. 72 , 664-72, (2014). Selling Leads | Chromatogr., 437, 1988, 33-45. umn class: Standard polar; Column length: 2 m; Column type: Packed; Start T: 100 C; CAS no: 74884; Active phase: Carbowax 20M; Data type: Kovats RI; Authors: Rohrschneider, L., Eine methode zur charakterisierung von gaschromatographischen trennflussigkeiten, J. 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Shoes immediately CAS No iodomethane melting point in May, 2011 deliver a methyl 8201 PC (! 1 ton super sacks in full container ( iodomethane melting point ) or truck load ( T/L ).! T/L ) quantities thermal analysis most frequently used to characterize solid crystalline materials Formula 13. Super sacks in full container ( FCL ) or truck load ( ). Http: //www.docbrown.info/page13/ChemicalTests/ChemicalTestsf.htm Learn with flashcards, games, iodomethane melting point the remaining case of skin off. Precautions for safe handlingAvoid contact with skin Causes skin irritation Causes serious irritation... Environmental fate, eco-toxicity and human health issues definitive test for any likely!